Ontology highlight
ABSTRACT:
SUBMITTER: Chen M
PROVIDER: S-EPMC2682698 | biostudies-literature | 2009 Mar
REPOSITORIES: biostudies-literature
Archives of biochemistry and biophysics 20081227 1
Theoretical and in vitro experiments suggest that protein folding cores form early in the process of folding, and that proteins may have evolved to optimize both folding speed and native-state stability. In our previous work (Chen et al., Structure, 14 (2006) 1401), we developed a set of empirical potential functions and used them to analyze interaction energies among secondary-structure elements in two beta-sandwich proteins. Our work on this group of proteins demonstrated that the predicted fo ...[more]