The CCN family of proteins: structure-function relationships.
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ABSTRACT:
SUBMITTER: Holbourn KP
PROVIDER: S-EPMC2683937 | biostudies-literature | 2008 Oct
REPOSITORIES: biostudies-literature
Publications
The CCN family of proteins: structure-function relationships.
Holbourn Kenneth P KP Acharya K Ravi KR Perbal Bernard B
Trends in biochemical sciences 20080911 10
The CCN proteins are key signalling and regulatory molecules involved in many vital biological functions, including cell proliferation, angiogenesis, tumourigenesis and wound healing. How these proteins influence such a range of functions remains incompletely understood but is probably related to their discrete modular nature and a complex array of intra- and inter-molecular interactions with a variety of regulatory proteins and ligands. Although certain aspects of their biology can be attribute ...[more]
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