Ontology highlight
ABSTRACT:
SUBMITTER: Demirci H
PROVIDER: S-EPMC2684062 | biostudies-literature | 2008 Jul
REPOSITORIES: biostudies-literature
Demirci Hasan H Gregory Steven T ST Dahlberg Albert E AE Jogl Gerwald G
Structure (London, England : 1993) 20080701 7
Ribosomal protein L11 is a universally conserved component of the large subunit, and plays a significant role during initiation, elongation, and termination of protein synthesis. In Escherichia coli, the lysine methyltransferase PrmA trimethylates the N-terminal alpha-amino group and the epsilon-amino groups of Lys3 and Lys39. Here, we report four PrmA-L11 complex structures in different orientations with respect to the PrmA active site. Two structures capture the L11 N-terminal alpha-amino grou ...[more]