Differential gene expression signatures for cell wall integrity found in chitin synthase II (chs2Delta) and myosin II (myo1Delta) deficient cytokinesis mutants of Saccharomyces cerevisiae.
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SUBMITTER: Rodriguez-Quinones JF
PROVIDER: S-EPMC2684100 | biostudies-literature | 2009 May
REPOSITORIES: biostudies-literature
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Differential gene expression signatures for cell wall integrity found in chitin synthase II (chs2Delta) and myosin II (myo1Delta) deficient cytokinesis mutants of Saccharomyces cerevisiae.
Rodríguez-Quiñones José F JF Rodríguez-Medina José R JR
BMC research notes 20090509
<h4>Background</h4>Myosin II-dependent contraction of the cytokinetic ring and primary septum formation by chitin synthase II are interdependent processes during cytokinesis in Saccharomyces cerevisiae. Hence, null mutants of myosin II (myo1Delta) and chitin synthase II (chs2Delta) share multiple morphological and molecular phenotypes. To understand the nature of their interdependent functions, we will seek to identify genes undergoing transcriptional regulation in chs2Delta strains and to estab ...[more]
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