Classification and regression tree (CART) analyses of genomic signatures reveal sets of tetramers that discriminate temperature optima of archaea and bacteria.
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ABSTRACT:
SUBMITTER: Dyer BD
PROVIDER: S-EPMC2685595 | biostudies-literature | 2008 Dec
REPOSITORIES: biostudies-literature
Publications
Classification and regression tree (CART) analyses of genomic signatures reveal sets of tetramers that discriminate temperature optima of archaea and bacteria.
Dyer Betsey Dexter BD Kahn Michael J MJ Leblanc Mark D MD
Archaea (Vancouver, B.C.) 20081201 3
Classification and regression tree (CART) analysis was applied to genome-wide tetranucleotide frequencies (genomic signatures) of 195 archaea and bacteria. Although genomic signatures have typically been used to classify evolutionary divergence, in this study, convergent evolution was the focus. Temperature optima for most of the organisms examined could be distinguished by CART analyses of tetranucleotide frequencies. This suggests that pervasive (nonlinear) qualities of genomes may reflect cer ...[more]
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