Ontology highlight
ABSTRACT:
SUBMITTER: Willett CG
PROVIDER: S-EPMC2686127 | biostudies-literature | 2007 May
REPOSITORIES: biostudies-literature
Willett Christopher G CG Duda Dan G DG di Tomaso Emmanuelle E Boucher Yves Y Czito Brian G BG Vujaskovic Zeljko Z Vlahovic Gordana G Bendell Johanna J Cohen Kenneth S KS Hurwitz Herbert I HI Bentley Rex R Lauwers Gregory Y GY Poleski Martin M Wong Terence Z TZ Paulson Erik E Ludwig Kirk A KA Jain Rakesh K RK
Nature clinical practice. Oncology 20070501 5
<h4>Background</h4>Localized rectal cancer responds well to 5-fluorouracil and radiation-based regimens. A phase I-II trial is currently testing the efficacy of adding bevacizumab, a VEGF-specific antibody, to standard chemoradiotherapy. The case presented here is a complete pathological response seen in a patient with extensive and locally invasive carcinoma after receiving this combined treatment.<h4>Investigations</h4>Physical examination, rectal ultrasound, PET-CT scan, laboratory tests, pro ...[more]