Ontology highlight
ABSTRACT:
SUBMITTER: Ribeiro L
PROVIDER: S-EPMC2686836 | biostudies-literature | 2007 Aug
REPOSITORIES: biostudies-literature
Ribeiro Luciana L Busnello João V JV Cantor Rita M RM Whelan Fiona F Whittaker Pamela P Deloukas Panos P Wong Ma-Li ML Licinio Julio J
Neuroreport 20070801 12
The hypothesis that brain-derived neurotrophic factor (BDNF) is involved in the pathogenesis of major depression is supported by several research findings; however, genetic studies assessing the relationship between BDNF and psychiatric disorders have produced conflicting results. We examined the effect of a BDNF polymorphism on depression susceptibility in Mexican-Americans. The single nucleotide polymorphism (Val66Met), which has been shown to have functional and behavioral effects, was genoty ...[more]