Ontology highlight
ABSTRACT:
SUBMITTER: Lhuillier S
PROVIDER: S-EPMC2689013 | biostudies-literature | 2009 May
REPOSITORIES: biostudies-literature
Proceedings of the National Academy of Sciences of the United States of America 20090511 21
In many bacterial viruses and in certain animal viruses, the double-stranded DNA genome enters and exits the capsid through a portal gatekeeper. We report a pseudoatomic structure of a complete portal system. The bacteriophage SPP1 gatekeeper is composed of dodecamers of the portal protein gp6, the adaptor gp15, and the stopper gp16. The solution structures of gp15 and gp16 were determined by NMR. They were then docked together with the X-ray structure of gp6 into the electron density of the app ...[more]