CPEB3 is associated with human episodic memory.
Ontology highlight
ABSTRACT:
SUBMITTER: Vogler C
PROVIDER: S-EPMC2691156 | biostudies-literature | 2009
REPOSITORIES: biostudies-literature
Publications
CPEB3 is associated with human episodic memory.
Vogler Christian C Spalek Klara K Aerni Amanda A Demougin Philippe P Müller Ariane A Huynh Kim-Dung KD Papassotiropoulos Andreas A de Quervain Dominique J-F DJ
Frontiers in behavioral neuroscience 20090504
Cytoplasmic polyadenylation element-binding (CPEB) proteins are crucial for synaptic plasticity and memory in model organisms. A highly conserved, mammalian-specific short intronic sequence within CPEB3 has been identified as a ribozyme with self-cleavage properties. In humans, the ribozyme sequence is polymorphic and harbors a single nucleotide polymorphism that influences cleavage activity of the ribozyme. Here we show that this variation is related to performance in an episodic memory task an ...[more]
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