Ontology highlight
ABSTRACT:
SUBMITTER: Nern A
PROVIDER: S-EPMC2692379 | biostudies-literature | 2008 Apr
REPOSITORIES: biostudies-literature
Nern Aljoscha A Zhu Yan Y Zipursky S Lawrence SL
Neuron 20080401 1
The organization of neuronal processes into a series of layers is a hallmark of many brain regions. Homophilic cell adhesion molecules of the cadherin family have been implicated in layer choice. How they contribute to the targeting of neurons to distinct layers remains unclear. Here we systematically explore the role of a classical cadherin, Drosophila N-cadherin (CadN), in the targeting of five classes of related neurons to a series of consecutive layers in the fly visual system. We show that ...[more]