Genetic variation in DNA repair pathway genes and premenopausal breast cancer risk.
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ABSTRACT:
SUBMITTER: Han J
PROVIDER: S-EPMC2693208 | biostudies-literature | 2009 Jun
REPOSITORIES: biostudies-literature
Publications
Genetic variation in DNA repair pathway genes and premenopausal breast cancer risk.
Han Jiali J Haiman Christopher C Niu Tianhua T Guo Qun Q Cox David G DG Willett Walter C WC Hankinson Susan E SE Hunter David J DJ
Breast cancer research and treatment 20080613 3
<h4>Purpose</h4>We comprehensively evaluated genetic variants in DNA repair genes with premenopausal breast cancer risk.<h4>Methods</h4>In this nested case-control study of 239 prospectively ascertained premenopausal breast cancer cases and 477 matched controls within the Nurses' Health Study II, we evaluated 1,463 genetic variants in 60 candidate genes across five DNA repair pathways, along with DNA polymerases, Fanconi Anemia complementation groups, and other related genes.<h4>Results</h4>Four ...[more]
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