Ontology highlight
ABSTRACT:
SUBMITTER: Stranahan AM
PROVIDER: S-EPMC2694409 | biostudies-literature | 2008
REPOSITORIES: biostudies-literature
Stranahan Alexis M AM Norman Eric D ED Lee Kim K Cutler Roy G RG Telljohann Richard S RS Egan Josephine M JM Mattson Mark P MP
Hippocampus 20080101 11
Overall dietary energy intake, particularly the consumption of simple sugars such as fructose, has been increasing steadily in Western societies, but the effects of such diets on the brain are poorly understood. Here, we used functional and structural assays to characterize the effects of excessive caloric intake on the hippocampus, a brain region important for learning and memory. Rats fed with a high-fat, high-glucose diet supplemented with high-fructose corn syrup showed alterations in energy ...[more]