Ontology highlight
ABSTRACT:
SUBMITTER: Drew CF
PROVIDER: S-EPMC2696204 | biostudies-literature | 2007 May
REPOSITORIES: biostudies-literature
Drew Caroline F CF Lin Chih Min CM Jiang Ting Xin TX Blunt Geoff G Mou Chunyan C Chuong Cheng Ming CM Headon Denis J DJ
Developmental biology 20070216 1
A subgroup of the TNF receptor family, composed of Edar, Troy and Xedar, are implicated in the development of ectodermal appendages, such as hair follicles, teeth and sweat glands. We have isolated chicken orthologues of these three receptors and analysed their roles in early feather development. Conservation of protein sequences between mammalian and avian proteins is variable, with avian Edar showing the greatest degree of sequence identity. cXedar differs from its mammalian orthologue in that ...[more]