Ontology highlight
ABSTRACT:
SUBMITTER: Dreher SD
PROVIDER: S-EPMC2696385 | biostudies-literature | 2009 May
REPOSITORIES: biostudies-literature
The Journal of organic chemistry 20090501 10
Parallel microscale experimentation was used to develop general conditions for the Suzuki-Miyaura cross-coupling of diversely functionalized primary alkyltrifluoroborates with a variety of aryl chlorides. These conditions were found to be amenable to coupling with aryl bromides, iodides, and triflates as well. The conditions that were previously identified through similar techniques to promote the cross-coupling of secondary alkyltrifluoroborates with aryl chlorides were not optimal for the prim ...[more]