Unknown

Dataset Information

0

Molecular characterization and tissue localization of an F-box only protein from silkworm, Bombyx mori.


ABSTRACT: The eukaryotic F-box protein family is characterized by an F-box motif that has been shown to be critical for the controlled degradation of regulatory proteins. We identified a gene encoding an F-box protein from a cDNA library of silkworm pupae, which has an ORF of 1821 bp, encoding a predicted 606 amino acids. Bioinformatic analysis on the amino acid sequence shows that BmFBXO21 has a low degree of similarity to proteins from other species, and may be related to the regulation of cell-cycle progression. We have detected the expression pattern of BmFBXO21 mRNA and protein and performed immunohistochemistry at three different levels. Expression was highest in the spinning stage, and in the tissues of head, epidermis, and genital organs.

SUBMITTER: Shen Y 

PROVIDER: S-EPMC2699434 | biostudies-literature | 2009

REPOSITORIES: biostudies-literature

altmetric image

Publications

Molecular characterization and tissue localization of an F-box only protein from silkworm, Bombyx mori.

Shen Yafang Y   Zhang Tiancheng T   Chen Jianqing J   Lv Zhengbing Z   Chen Jian J   Wang Dan D   Nie Zuoming Z   He Pingan P   Wang Jiang J   Zheng Qingliang Q   Sheng Qing Q   Wu Xiangfu X   Zhang Yaozhou Y  

Comparative and functional genomics 20090614


The eukaryotic F-box protein family is characterized by an F-box motif that has been shown to be critical for the controlled degradation of regulatory proteins. We identified a gene encoding an F-box protein from a cDNA library of silkworm pupae, which has an ORF of 1821 bp, encoding a predicted 606 amino acids. Bioinformatic analysis on the amino acid sequence shows that BmFBXO21 has a low degree of similarity to proteins from other species, and may be related to the regulation of cell-cycle pr  ...[more]

Similar Datasets

| S-EPMC6503385 | biostudies-literature
| S-EPMC4608725 | biostudies-literature
| S-EPMC4522720 | biostudies-literature
| S-EPMC5855749 | biostudies-literature
| S-EPMC3937576 | biostudies-literature
| S-EPMC3040484 | biostudies-literature
| S-EPMC3732266 | biostudies-literature
| S-EPMC2396236 | biostudies-literature
| S-EPMC514797 | biostudies-literature
| S-EPMC8228281 | biostudies-literature