Ontology highlight
ABSTRACT:
SUBMITTER: Chen C
PROVIDER: S-EPMC2699515 | biostudies-literature | 2009 Jun
REPOSITORIES: biostudies-literature
Chen Chunlai C Wang Wenjuan W Ge Jing J Zhao Xin Sheng XS
Nucleic acids research 20090420 11
Hybridization of single-stranded DNA immobilized on the surface of gold nanoparticles (GNPs) into double stranded DNA and its subsequent dissociation into ssDNA were investigated. Melting curves and rates of dissociation and hybridization were measured using fluorescence detection based on hybridization-induced fluorescence change. Two distribution functions, namely the state distribution and the rate distribution, were proposed in order to take interfacial heterogeneity into account and to quan ...[more]