Dataset Information

The bioactivity of plant extracts against representative bacterial pathogens of the lower respiratory tract.

ABSTRACT:

Background

Lower respiratory tract infections are a major cause of illness and death. Such infections are common in intensive care units (ICU) and their lethality persists despite advances in diagnosis, treatment and prevention. In Mexico, some plants are used in traditional medicine to treat respiratory diseases or ailments such as cough, bronchitis, tuberculosis and other infections. Medical knowledge derived from traditional societies has motivated searches for new bioactive molecules derived from plants that show potent activity against bacterial pathogens. Therefore, the aim of this study was to evaluate the effect of hexanic, chloroformic (CLO), methanolic (MET) and aqueous extracts from various plants used in Mexican traditional medicine on various microorganisms associated with respiratory disease.

Methods

thirty-five extracts prepared from nine plants used in Mexican traditional medicine for the treatment of respiratory infections were evaluated against 15 control bacterial species and clinical isolates.

Results

Both chloroformic (CLO) and methanolic (MET) extracts of Larrea tridentata were active against Methicillin-resistant S. aureus, B. subtilis and L. monocytogenes. A MET extract of L. tridentata was also active against S. aureus, S. pneumoniae, S. maltophilia, E. faecalis and H. influenzae and the CLO extract was active against A. baumannii. An Aqueous extract of M. acumitata and a MET extract of N. officinale were active against S. pneumoniae. CLO and MET extracts of L. tridentata were active against clinical isolates of S. aureus, S. pneumoniae and E. faecalis.

Conclusion

Overall, our results support the potential use of L. tridentata as a source of antibacterial compounds.

SUBMITTER: Bocanegra-Garcia V

PROVIDER: S-EPMC2702266 | biostudies-literature | 2009 Jun

REPOSITORIES: biostudies-literature

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The bioactivity of plant extracts against representative bacterial pathogens of the lower respiratory tract.

Bocanegra-García Virgilio V Del Rayo Camacho-Corona María M Ramírez-Cabrera Mónica M Rivera Gildardo G Garza-González Elvira E

BMC research notes 20090601

<h4>Background</h4>Lower respiratory tract infections are a major cause of illness and death. Such infections are common in intensive care units (ICU) and their lethality persists despite advances in diagnosis, treatment and prevention. In Mexico, some plants are used in traditional medicine to treat respiratory diseases or ailments such as cough, bronchitis, tuberculosis and other infections. Medical knowledge derived from traditional societies has motivated searches for new bioactive molecules ...[more]

PMID: 19486533

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Dataset Information

The bioactivity of plant extracts against representative bacterial pathogens of the lower respiratory tract.

Background

Methods

Results

Conclusion

Publications

The bioactivity of plant extracts against representative bacterial pathogens of the lower respiratory tract.

Similar Datasets

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