Ontology highlight
ABSTRACT:
SUBMITTER: Tan RK
PROVIDER: S-EPMC2702770 | biostudies-literature | 2008 Aug
REPOSITORIES: biostudies-literature
Tan Robert K-Z RK Devkota Batsal B Harvey Stephen C SC
Journal of structural biology 20080516 2
The structures of large macromolecular complexes in different functional states can be determined by cryo-electron microscopy, which yields electron density maps of low to intermediate resolutions. The maps can be combined with high-resolution atomic structures of components of the complex, to produce a model for the complex that is more accurate than the formal resolution of the map. To this end, methods have been developed to dock atomic models into density maps rigidly or flexibly, and to ref ...[more]