Ontology highlight
ABSTRACT:
SUBMITTER: Yassai MB
PROVIDER: S-EPMC2706371 | biostudies-literature | 2009 Jul
REPOSITORIES: biostudies-literature
Yassai Maryam B MB Naumov Yuri N YN Naumova Elena N EN Gorski Jack J
Immunogenetics 20090701 7
T cell receptor (TCR) nucleotide sequences are often generated during analyses of T cell responses to pathogens or autoantigens. The most important region of the TCR is the third complementarity-determining region (CDR3) whose nucleotide sequence is unique to each T cell clone. The CDR3 interacts with the peptide and thus is important for recognizing pathogen or autoantigen epitopes. While conventions exist for identifying the various TCR chains, there is a lack of a concise nomenclature that wo ...[more]