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Broad-spectrum antimicrobial epiphytic and endophytic fungi from marine organisms: isolation, bioassay and taxonomy.


ABSTRACT: In the search for new marine derived antibiotics, 43 epi- and endophytic fungal strains were isolated from the surface or the inner tissue of different marine plants and invertebrates. Through preliminary and secondary screening, 10 of them were found to be able to produce broad-spectrum antimicrobial metabolites. By morphological and molecular biological methods, three active strains were characterized to be Penicillium glabrum, Fusarium oxysporum, and Alternaria alternata.

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC2707037 | biostudies-literature | 2009

REPOSITORIES: biostudies-literature

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Broad-spectrum antimicrobial epiphytic and endophytic fungi from marine organisms: isolation, bioassay and taxonomy.

Zhang Yi Y   Mu Jun J   Feng Yan Y   Kang Yue Y   Zhang Jia J   Gu Peng-Juan PJ   Wang Yu Y   Ma Li-Fang LF   Zhu Yan-Hua YH  

Marine drugs 20090417 2


In the search for new marine derived antibiotics, 43 epi- and endophytic fungal strains were isolated from the surface or the inner tissue of different marine plants and invertebrates. Through preliminary and secondary screening, 10 of them were found to be able to produce broad-spectrum antimicrobial metabolites. By morphological and molecular biological methods, three active strains were characterized to be Penicillium glabrum, Fusarium oxysporum, and Alternaria alternata. ...[more]

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