Ontology highlight
ABSTRACT:
SUBMITTER: Dijkman R
PROVIDER: S-EPMC2708629 | biostudies-literature | 2009 Aug
REPOSITORIES: biostudies-literature
Dijkman Ronald R Koekkoek Sylvie M SM Molenkamp Richard R Schildgen Oliver O van der Hoek Lia L
Journal of virology 20090527 15
In 2005, a human bocavirus was discovered in children with respiratory tract illnesses. Attempts to culture this virus on conventional cell lines has failed thus far. We investigated whether the virus can replicate on pseudostratified human airway epithelium. This cell culture system mimics the human airway environment and facilitates culturing of various respiratory agents. The cells were inoculated with human bocavirus-positive nasopharyngeal washes from children, and virus replication was mon ...[more]