Tools for exploring the proteomosphere.
Ontology highlight
ABSTRACT:
SUBMITTER: Shevchenko A
PROVIDER: S-EPMC2713397 | biostudies-literature | 2009 Mar
REPOSITORIES: biostudies-literature
Publications
Tools for exploring the proteomosphere.
Shevchenko Andrej A Valcu Cristina-Maria CM Junqueira Magno M
Journal of proteomics 20090122 2
Homology-driven proteomics aims at exploring the proteomes of organisms with unsequenced genomes that, despite rapid genomic sequencing progress, still represent the overwhelming majority of species in the biosphere. Methodologies have been developed to enable automated LC-MS/MS identifications of unknown proteins, which rely on the sequence similarity between the fragmented peptides and reference database sequences from phylogenetically related species. However, because full sequences of matche ...[more]
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