Ontology highlight
ABSTRACT:
SUBMITTER: Ding X
PROVIDER: S-EPMC2715284 | biostudies-literature | 2009 Jan
REPOSITORIES: biostudies-literature
Ding Xiaoyan X Patel Mrinali M Chan Chi-Chao CC
Progress in retinal and eye research 20081106 1
Age-related macular degeneration (AMD) is a leading cause of irreversible blindness in the world. Although the etiology and pathogenesis of AMD remain largely unclear, a complex interaction of genetic and environmental factors is thought to exist. AMD pathology is characterized by degeneration involving the retinal photoreceptors, retinal pigment epithelium, and Bruch's membrane, as well as, in some cases, alterations in choroidal capillaries. Recent research on the genetic and molecular underpi ...[more]