OqxAB encoding a multidrug efflux pump in human clinical isolates of Enterobacteriaceae.
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ABSTRACT:
SUBMITTER: Kim HB
PROVIDER: S-EPMC2715617 | biostudies-literature | 2009 Aug
REPOSITORIES: biostudies-literature
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oqxAB encoding a multidrug efflux pump in human clinical isolates of Enterobacteriaceae.
Kim Hong Bin HB Wang Minghua M Park Chi Hye CH Kim Eui-Chong EC Jacoby George A GA Hooper David C DC
Antimicrobial agents and chemotherapy 20090615 8
The genes for multidrug efflux pump OqxAB, which is active on fluoroquinolones, were found in human clinical isolates on a plasmid in Escherichia coli and on the chromosome of Klebsiella pneumoniae. IS26-like sequences flanked the plasmid-mediated oqxAB genes, suggesting that they had been mobilized as part of a composite transposon. ...[more]
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