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GES-11, a novel integron-associated GES variant in Acinetobacter baumannii.

ABSTRACT: New extended-spectrum beta-lactamase GES-11 was detected in Acinetobacter baumannii BM4674. The enzyme conferred resistance to beta-lactams, including aztreonam, and reduced susceptibility to carbapenems. The structural gene was part of a class 1 integron borne by self-transferable plasmid pIP847. GES-type beta-lactamases have not been reported previously in A. baumannii.

SUBMITTER: Moubareck C 

PROVIDER: S-EPMC2715621 | biostudies-literature | 2009 Aug

REPOSITORIES: biostudies-literature

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GES-11, a novel integron-associated GES variant in Acinetobacter baumannii.

Moubareck Carole C   Brémont Sylvie S   Conroy Marie-Christine MC   Courvalin Patrice P   Lambert Thierry T  

Antimicrobial agents and chemotherapy 20090518 8

New extended-spectrum beta-lactamase GES-11 was detected in Acinetobacter baumannii BM4674. The enzyme conferred resistance to beta-lactams, including aztreonam, and reduced susceptibility to carbapenems. The structural gene was part of a class 1 integron borne by self-transferable plasmid pIP847. GES-type beta-lactamases have not been reported previously in A. baumannii. ...[more]

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