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Intraspecies signaling involving the diffusible signal factor BDSF (cis-2-dodecenoic acid) influences virulence in Burkholderia cenocepacia.

ABSTRACT: Burkholderia cenocepacia produces a diffusible fatty acid signal molecule, cis-2-dodecenoic acid (BDSF), that has been implicated in interspecies and interkingdom communication. Here, we show that BDSF also acts as an intraspecies signal in B. cenocepacia to control factors contributing to virulence of this major opportunistic pathogen.

SUBMITTER: Ryan RP 

PROVIDER: S-EPMC2715730 | biostudies-literature | 2009 Aug

REPOSITORIES: biostudies-literature

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Intraspecies signaling involving the diffusible signal factor BDSF (cis-2-dodecenoic acid) influences virulence in Burkholderia cenocepacia.

Ryan Robert P RP   McCarthy Yvonne Y   Watt Steven A SA   Niehaus Karsten K   Dow J Maxwell JM  

Journal of bacteriology 20090529 15

Burkholderia cenocepacia produces a diffusible fatty acid signal molecule, cis-2-dodecenoic acid (BDSF), that has been implicated in interspecies and interkingdom communication. Here, we show that BDSF also acts as an intraspecies signal in B. cenocepacia to control factors contributing to virulence of this major opportunistic pathogen. ...[more]

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