Ontology highlight
ABSTRACT:
SUBMITTER: Ratnakar SJ
PROVIDER: S-EPMC2716115 | biostudies-literature | 2008 Jan
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20071208 1
The chemical exchange saturation transfer (CEST) efficiency for a series Eu3+-based tetraamide complexes bearing p-substituents on a single coordinating pendant arm is highly sensitive to water exchange rates. The CEST effect increases in the order Me < MeO < F approximately CO2tBu < CN < H. These results show that CEST contrast can be modulated by changes in electron density at a single ligating atom, and this forms the basis of creating imaging agents that respond to chemical oxidation and red ...[more]