Creation and implications of a phenome-genome network.
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ABSTRACT:
SUBMITTER: Butte AJ
PROVIDER: S-EPMC2716377 | biostudies-literature | 2006 Jan
REPOSITORIES: biostudies-literature
Publications
Creation and implications of a phenome-genome network.
Butte Atul J AJ Kohane Isaac S IS
Nature biotechnology 20060101 1
Although gene and protein measurements are increasing in quantity and comprehensiveness, they do not characterize a sample's entire phenotype in an environmental or experimental context. Here we comprehensively consider associations between components of phenotype, genotype and environment to identify genes that may govern phenotype and responses to the environment. Context from the annotations of gene expression data sets in the Gene Expression Omnibus is represented using the Unified Medical L ...[more]
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