Ontology highlight
ABSTRACT:
SUBMITTER: Lee H
PROVIDER: S-EPMC2718371 | biostudies-literature | 2009 Jul
REPOSITORIES: biostudies-literature
Lee Hakho H Yoon Tae-Jong TJ Figueiredo Jose-Luiz JL Swirski Filip K FK Weissleder Ralph R
Proceedings of the National Academy of Sciences of the United States of America 20090720 30
There is a growing need for fast, highly sensitive and quantitative technologies to detect and profile unaltered cells in biological samples. Technologies in current clinical use are often time consuming, expensive, or require considerable sample sizes. Here, we report a diagnostic magnetic resonance (DMR) sensor that combines a miniaturized NMR probe with targeted magnetic nanoparticles for detection and molecular profiling of cancer cells. The sensor measures the transverse relaxation rate of ...[more]