Dataset Information
DeconMSn: a software tool for accurate parent ion monoisotopic mass determination for tandem mass spectra.
Ontology highlight
ABSTRACT: Unlabelled
DeconMSn accurately determines the monoisotopic mass and charge state of parent ions from high-resolution tandem mass spectrometry data, offering significant improvement for LTQ_FT and LTQ_Orbitrap instruments over the commercially delivered Thermo Fisher Scientific's extract_msn tool. Optimal parent ion mass tolerance values can be determined using accurate mass information, thus improving peptide identifications for high-mass measurement accuracy experiments. For low-resolution data from LCQ and LTQ instruments, DeconMSn incorporates a support-vector-machine-based charge detection algorithm that identifies the most likely charge of a parent species through peak characteristics of its fragmentation pattern.Availability
http://ncrr.pnl.gov/software/ or http://www.proteomicsresource.org/.
SUBMITTER: Mayampurath AM
PROVIDER: S-EPMC2720627 | biostudies-literature | 2008 Apr
REPOSITORIES: biostudies-literature
Publications
DeconMSn: a software tool for accurate parent ion monoisotopic mass determination for tandem mass spectra.
Bioinformatics (Oxford, England) 20080226 7
<h4>Unlabelled</h4>DeconMSn accurately determines the monoisotopic mass and charge state of parent ions from high-resolution tandem mass spectrometry data, offering significant improvement for LTQ_FT and LTQ_Orbitrap instruments over the commercially delivered Thermo Fisher Scientific's extract_msn tool. Optimal parent ion mass tolerance values can be determined using accurate mass information, thus improving peptide identifications for high-mass measurement accuracy experiments. For low-resolut ...[more]