Ontology highlight
ABSTRACT:
SUBMITTER: Qiu P
PROVIDER: S-EPMC2720937 | biostudies-literature | 2009
REPOSITORIES: biostudies-literature
Qiu Ping P Cai Xiao-Yan XY Ding Wei W Zhang Qing Q Norris Ellie D ED Greene Jonathan R JR
Journal of biomedical science 20090708
The genotype of Hepatitis C Virus (HCV) strains is an important determinant of the severity and aggressiveness of liver infection as well as patient response to antiviral therapy. Fast and accurate determination of viral genotype could provide direction in the clinical management of patients with chronic HCV infections. Using publicly available HCV nucleotide sequences, we built a global Position Weight Matrix (PWM) for the HCV genome. Based on the PWM, a set of genotype specific nucleotide sequ ...[more]