Ontology highlight
ABSTRACT:
SUBMITTER: Martin C
PROVIDER: S-EPMC2722682 | biostudies-literature | 2009 May
REPOSITORIES: biostudies-literature
Martin Catherine C Chen Songbi S Maya-Mendoza Apolinar A Lovric Josip J Sims Paul F G PF Jackson Dean A DA
Journal of cell science 20090421 Pt 10
The dynamic ability of genomes to interact with discrete nuclear compartments appears to be essential for chromatin function. However, the extent to which structural nuclear proteins contribute to this level of organization is largely unresolved. To test the links between structure and function, we evaluated how nuclear lamins contribute to the organization of a major functional compartment, the nucleolus. HeLa cells with compromised expression of the genes encoding lamins were analyzed using hi ...[more]