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Neuraminidase inhibitors for treatment and prophylaxis of influenza in children: systematic review and meta-analysis of randomised controlled trials.


ABSTRACT: To assess the effects of the neuraminidase inhibitors oseltamivir and zanamivir in treatment of children with seasonal influenza and prevention of transmission to children in households.Systematic review and meta-analysis of data from published and unpublished randomised controlled trials.Medline and Embase to June 2009, trial registries, and manufacturers and authors of relevant studies. Review methods Eligible studies were randomised controlled trials of neuraminidase inhibitors in children aged

SUBMITTER: Shun-Shin M 

PROVIDER: S-EPMC2724601 | biostudies-literature | 2009 Aug

REPOSITORIES: biostudies-literature

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Neuraminidase inhibitors for treatment and prophylaxis of influenza in children: systematic review and meta-analysis of randomised controlled trials.

Shun-Shin Matthew M   Thompson Matthew M   Heneghan Carl C   Perera Rafael R   Harnden Anthony A   Mant David D  

BMJ (Clinical research ed.) 20090810


<h4>Objective</h4>To assess the effects of the neuraminidase inhibitors oseltamivir and zanamivir in treatment of children with seasonal influenza and prevention of transmission to children in households.<h4>Design</h4>Systematic review and meta-analysis of data from published and unpublished randomised controlled trials.<h4>Data sources</h4>Medline and Embase to June 2009, trial registries, and manufacturers and authors of relevant studies. Review methods Eligible studies were randomised contro  ...[more]

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