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Folding DNA origami from a double-stranded source of scaffold.


ABSTRACT: Combined heat and chemical denaturation of double-stranded DNA scaffold strands in the presence of staple strands, followed by a sudden temperature drop and then stepwise dialysis to remove the chemical denaturant, leads to self-assembly of two distinct DNA-origami structures.

SUBMITTER: Hogberg B 

PROVIDER: S-EPMC2724999 | biostudies-literature | 2009 Jul

REPOSITORIES: biostudies-literature

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Folding DNA origami from a double-stranded source of scaffold.

Högberg Björn B   Liedl Tim T   Shih William M WM  

Journal of the American Chemical Society 20090701 26


Combined heat and chemical denaturation of double-stranded DNA scaffold strands in the presence of staple strands, followed by a sudden temperature drop and then stepwise dialysis to remove the chemical denaturant, leads to self-assembly of two distinct DNA-origami structures. ...[more]

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