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What happens when Trypanosoma brucei leaves Africa.


ABSTRACT: Julius Lukes and co-workers evaluated the evolutionary origin of Trypanosoma equiperdum and Trypanosoma evansi, parasites that cause horse and camel diseases. Although similar to T. brucei, the sleeping-sickness parasite, these trypanosomes do not cycle through the tsetse fly and have been able to spread beyond Africa. Transmission occurs sexually, or via blood-sucking flies or vampire bats. They concluded that these parasites, which resemble yeast petite mutants, are T. brucei sub-species, which have evolved recently through changes in mitochondrial DNA.

SUBMITTER: Jensen RE 

PROVIDER: S-EPMC2725760 | biostudies-literature | 2008 Oct

REPOSITORIES: biostudies-literature

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What happens when Trypanosoma brucei leaves Africa.

Jensen Robert E RE   Simpson Larry L   Englund Paul T PT  

Trends in parasitology 20080818 10


Julius Lukes and co-workers evaluated the evolutionary origin of Trypanosoma equiperdum and Trypanosoma evansi, parasites that cause horse and camel diseases. Although similar to T. brucei, the sleeping-sickness parasite, these trypanosomes do not cycle through the tsetse fly and have been able to spread beyond Africa. Transmission occurs sexually, or via blood-sucking flies or vampire bats. They concluded that these parasites, which resemble yeast petite mutants, are T. brucei sub-species, whic  ...[more]

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