Ontology highlight
ABSTRACT:
SUBMITTER: Xu Q
PROVIDER: S-EPMC2726009 | biostudies-literature | 2009 Jul
REPOSITORIES: biostudies-literature
Xu Qingping Q Carlton Dennis D Miller Mitchell D MD Elsliger Marc-André MA Krishna S Sri SS Abdubek Polat P Astakhova Tamara T Burra Prasad P Chiu Hsiu-Ju HJ Clayton Thomas T Deller Marc C MC Duan Lian L Elias Ylva Y Feuerhelm Julie J Grant Joanna C JC Grzechnik Anna A Grzechnik Slawomir K SK Han Gye Won GW Jaroszewski Lukasz L Jin Kevin K KK Klock Heath E HE Knuth Mark W MW Kozbial Piotr P Kumar Abhinav A Marciano David D McMullan Daniel D Morse Andrew T AT Nigoghossian Edward E Okach Linda L Oommachen Silvya S Paulsen Jessica J Reyes Ron R Rife Christopher L CL Sefcovic Natasha N Trame Christine C Trout Christina V CV van den Bedem Henry H Weekes Dana D Hodgson Keith O KO Wooley John J Deacon Ashley M AM Godzik Adam A Lesley Scott A SA Wilson Ian A IA
Journal of molecular biology 20090518 4
Cell-cycle-regulated stalk biogenesis in Caulobacter crescentus is controlled by a multistep phosphorelay system consisting of the hybrid histidine kinase ShkA, the histidine phosphotransfer (HPt) protein ShpA, and the response regulator TacA. ShpA shuttles phosphoryl groups between ShkA and TacA. When phosphorylated, TacA triggers a downstream transcription cascade for stalk synthesis in an RpoN-dependent manner. The crystal structure of ShpA was determined to 1.52 A resolution. ShpA belongs to ...[more]