An expression screen for RhoGEF genes involved in C. elegans gonadogenesis.
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ABSTRACT:
SUBMITTER: Ziel JW
PROVIDER: S-EPMC2726742 | biostudies-literature | 2009 Sep
REPOSITORIES: biostudies-literature
Publications
An expression screen for RhoGEF genes involved in C. elegans gonadogenesis.
Ziel Joshua W JW Matus David Q DQ Sherwood David R DR
Gene expression patterns : GEP 20090618 6
The gonad in Caenorhabditis elegans is an important model system for understanding complex morphogenetic processes including cellular movement, cell fusion, cell invasion and cell polarity during development. One class of signaling proteins known to be critical for the cellular events underlying morphogenesis is the Rho family GTPases, particularly RhoA, Rac and Cdc42. In C. elegans orthologues of these genes have been shown to be important for gonad development. In our current study we have ext ...[more]
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