Ontology highlight
ABSTRACT:
SUBMITTER: Yuen EY
PROVIDER: S-EPMC2729022 | biostudies-literature | 2009 Aug
REPOSITORIES: biostudies-literature
Yuen Eunice Y EY Liu Wenhua W Karatsoreos Ilia N IN Feng Jian J McEwen Bruce S BS Yan Zhen Z
Proceedings of the National Academy of Sciences of the United States of America 20090729 33
The prefrontal cortex (PFC), a key brain region controlling cognition and emotion, is strongly influenced by stress. While chronic stress often produces detrimental effects on these measures, acute stress has been shown to enhance learning and memory, predominantly through the action of corticosteroid stress hormones. We used a combination of electrophysiological, biochemical, and behavioral approaches in an effort to identify the cellular targets of acute stress. We found that behavioral stress ...[more]