Ontology highlight
ABSTRACT:
SUBMITTER: Oh YM
PROVIDER: S-EPMC2731854 | biostudies-literature | 2009
REPOSITORIES: biostudies-literature
Oh Young Min YM Kim Jong Kyoung JK Choi Yongwook Y Choi Seungjin S Yoo Joo-Yeon JY
PloS one 20090904 9
The comprehensive identification of functional transcription factor binding sites (TFBSs) is an important step in understanding complex transcriptional regulatory networks. This study presents a motif-based comparative approach, STAT-Finder, for identifying functional DNA binding sites of STAT3 transcription factor. STAT-Finder combines STAT-Scanner, which was designed to predict functional STAT TFBSs with improved sensitivity, and a motif-based alignment to minimize false positive prediction ra ...[more]