Ontology highlight
ABSTRACT:
SUBMITTER: Utama A
PROVIDER: S-EPMC2731954 | biostudies-literature | 2009 Aug
REPOSITORIES: biostudies-literature
Utama Andi A Purwantomo Sigit S Siburian Marlinang Diarta MD Dhenni Rama R Gani Rino Alvani RA Hasan Irsan I Sanityoso Andri A Miskad Upik Anderiani UA Akil Fardah F Yusuf Irawan I Achwan Wenny Astuti WA Soemohardjo Soewignjo S Lelosutan Syafruddin A R SA Martamala Ruswhandi R Lukito Benyamin B Budihusodo Unggul U Lesmana Laurentius Adrianus LA Sulaiman Ali A Tai Susan S
World journal of gastroenterology 20090801 32
<h4>Aim</h4>To identify the distribution of hepatitis B virus (HBV) subgenotype and basal core promoter (BCP) mutations among patients with HBV-associated liver disease in Indonesia.<h4>Methods</h4>Patients with chronic hepatitis (CH, n = 61), liver cirrhosis (LC, n = 62), and hepatocellular carcinoma (HCC, n = 48) were included in this study. HBV subgenotype was identified based on S or preS gene sequence, and mutations in the HBx gene including the overlapping BCP region were examined by direc ...[more]