Ontology highlight
ABSTRACT:
SUBMITTER: Ehn NL
PROVIDER: S-EPMC2734951 | biostudies-literature | 2007 Nov
REPOSITORIES: biostudies-literature
Pediatric research 20071101 5
Progesterone plays a critical role in the maintenance of pregnancy and has been effectively used to prevent recurrences of preterm labor. We investigated the role of genetic variation in the progesterone receptor (PGR) gene in modulating risks for preterm labor by examining both maternal and fetal effects. Cases were infants delivered prematurely at the University of Iowa. DNA was collected from the mother, infant, and father. Seventeen single nucleotide polymorphisms (SNP) and an insertion dele ...[more]