Ontology highlight
ABSTRACT:
SUBMITTER: Hong Y
PROVIDER: S-EPMC2735683 | biostudies-literature | 2009 Sep
REPOSITORIES: biostudies-literature
The Korean journal of parasitology 20090828 3
Trypanosoma brucei, a protozoan parasite, causes sleeping sickness in humans and Nagana disease in domestic animals in central Africa. The trypanosome surface is extensively covered by glycosylphosphatidylinositol (GPI)-anchored proteins known as variant surface glycoproteins and procyclins. GPI anchoring is suggested to be important for trypanosome survival and establishment of infection. Trypanosomes are not only pathogenically important, but also constitute a useful model for elucidating the ...[more]