Ontology highlight
ABSTRACT: Background
Acupuncture is widely used in China to treat functional dyspepsia (FD). However, its effectiveness in the treatment of FD, and whether FD-specific acupoints exist, are controversial. So this study aims to determine if acupuncture is an effective treatment for FD and if acupoint specificity exists according to traditional acupuncture meridians and acupoint theories.Design
This multicenter randomized controlled trial will include four acupoint treatment groups, one non-acupoint control group and one drug (positive control) group. The four acupoint treatment groups will focus on: (1) specific acupoints of the stomach meridian; (2) non-specific acupoints of the stomach meridian; (3) specific acupoints of alarm and transport points; and (4) acupoints of the gallbladder meridian. These four groups of acupoints are thought to differ in terms of clinical efficacy, according to traditional acupuncture meridians and acupoint theories. A total of 120 FD patients will be included in each group. Each patient will receive 20 sessions of acupuncture treatment over 4 weeks. The trial will be conducted in eight hospitals located in three centers of China. The primary outcomes in this trial will include differences in Nepean Dyspepsia Index scores and differences in the Symptom Index of Dyspepsia before randomization, 2 weeks and 4 weeks after randomization, and 1 month and 3 months after completing treatment.Discussion
The important features of this trial include the randomization procedures (controlled by a central randomization system), a standardized protocol of acupuncture manipulation, and the fact that this is the first multicenter randomized trial of FD and acupuncture to be performed in China. The results of this trial will determine whether acupuncture is an effective treatment for FD and whether using different acupoints or different meridians leads to differences in clinical efficacy.Trial registration number
Clinical Trials.gov Identifier: NCT00599677.
SUBMITTER: Zheng H
PROVIDER: S-EPMC2736949 | biostudies-literature | 2009 Aug
REPOSITORIES: biostudies-literature
Zheng Hui H Tian Xiao-ping XP Li Ying Y Liang Fan-rong FR Yu Shu-guang SG Liu Xu-guang XG Tang Yong Y Yang Xu-guang XG Yan Jie J Sun Guo-jie GJ Chang Xiao-rong XR Zhang Hong-xing HX Ma Ting-ting TT Yu Shu-yuan SY
Trials 20090823
<h4>Background</h4>Acupuncture is widely used in China to treat functional dyspepsia (FD). However, its effectiveness in the treatment of FD, and whether FD-specific acupoints exist, are controversial. So this study aims to determine if acupuncture is an effective treatment for FD and if acupoint specificity exists according to traditional acupuncture meridians and acupoint theories.<h4>Design</h4>This multicenter randomized controlled trial will include four acupoint treatment groups, one non-a ...[more]