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Region of difference 1 in nontuberculous Mycobacterium species adds a phylogenetic and taxonomical character.

ABSTRACT: The esat-6 and cfp-10 genes are essential for virulence in Mycobacterium tuberculosis. Among nontuberculous mycobacteria, we found these genes only in M. kansasii, M. szulgai, M. marinum, and M. riyadhense, with unique sequences. This adds a phylogenetic and taxonomical characteristic and may represent a virulence factor for nontuberculous mycobacteria.

SUBMITTER: van Ingen J

PROVIDER: S-EPMC2737943 | biostudies-literature | 2009 Sep

REPOSITORIES: biostudies-literature

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Region of difference 1 in nontuberculous Mycobacterium species adds a phylogenetic and taxonomical character.

van Ingen Jakko J de Zwaan Rina R Dekhuijzen Richard R Boeree Martin M van Soolingen Dick D

Journal of bacteriology 20090717 18

The esat-6 and cfp-10 genes are essential for virulence in Mycobacterium tuberculosis. Among nontuberculous mycobacteria, we found these genes only in M. kansasii, M. szulgai, M. marinum, and M. riyadhense, with unique sequences. This adds a phylogenetic and taxonomical characteristic and may represent a virulence factor for nontuberculous mycobacteria. ...[more]

PMID: 19617365

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