The CheZ binding interface of CheAS is located in alpha-helix E.
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ABSTRACT:
SUBMITTER: O'Connor C
PROVIDER: S-EPMC2737944 | biostudies-literature | 2009 Sep
REPOSITORIES: biostudies-literature
Publications
The CheZ binding interface of CheAS is located in alpha-helix E.
O'Connor Christopher C Matsumura Philip P Campos Andres A
Journal of bacteriology 20090706 18
Specific CheA-short (CheA(S)) residues, L123 and L126, were identified as critical for CheZ binding. In the CheA(S) 'P1-CheZ nuclear magnetic resonance structure, these residues form an interaction surface on alpha-helix E in the 'P1 domain. Both L123 and L126 are buried in CheA-long (CheA(L)), providing an explanation for why CheA(L) fails to bind CheZ. ...[more]
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