Ontology highlight
ABSTRACT:
SUBMITTER: Hsu K
PROVIDER: S-EPMC2738576 | biostudies-literature | 2009 Aug
REPOSITORIES: biostudies-literature
Hsu Kate K Chi Naiwen N Gucek Marjan M Van Eyk Jennifer E JE Cole Robert N RN Lin Marie M Foster D Brian DB
Blood 20090629 9
The special blood group antigen Mi.III exhibits a characteristic hybrid structure of glycophorin A (GPA) and glycophorin B, termed Gp.Mur. This phenotype has exceptionally high occurrence rates in several indigenous tribes in Taiwan ( approximately 21.2%-88.4%). Because glycophorin/Miltenberger begins interaction with anion exchanger-1 (AE1) in the endoplasmic reticulum, we hypothesized that the AE1-based macrocomplexes on erythrocyte membranes obtained from Mi.III(+) people could be differentia ...[more]