Reanalysis of Tyrannosaurus rex Mass Spectra.
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ABSTRACT:
SUBMITTER: Bern M
PROVIDER: S-EPMC2738754 | biostudies-literature | 2009 Sep
REPOSITORIES: biostudies-literature
Publications
Reanalysis of Tyrannosaurus rex Mass Spectra.
Bern Marshall M Phinney Brett S BS Goldberg David D
Journal of proteome research 20090901 9
Asara et al. reported the detection of collagen peptides in a 68-million-year-old Tyrannosaurus rex bone by shotgun proteomics. This finding has been called into question as a possible statistical artifact. We reanalyze Asara et al.'s tandem mass spectra using a different search engine and different statistical tools. Our reanalysis shows a sample containing common laboratory contaminants, soil bacteria, and bird-like hemoglobin and collagen. ...[more]
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