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Stereoselective synthesis of spirocyclic oxindoles via Prins cyclizations.

ABSTRACT: The synthesis of spirocyclic oxindole pyran and oxepene frameworks using highly stereoselective Prins cyclizations of homoallylic and bis-homoallylic alcohols and isatin ketals is described.

SUBMITTER: Castaldi MP

PROVIDER: S-EPMC2739092 | biostudies-literature | 2009 Aug

REPOSITORIES: biostudies-literature

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Stereoselective synthesis of spirocyclic oxindoles via Prins cyclizations.

Castaldi M Paola MP Troast Dawn M DM Porco John A JA

Organic letters 20090801 15

The synthesis of spirocyclic oxindole pyran and oxepene frameworks using highly stereoselective Prins cyclizations of homoallylic and bis-homoallylic alcohols and isatin ketals is described. ...[more]

PMID: 19719184

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