Ontology highlight
ABSTRACT:
SUBMITTER: Bick MJ
PROVIDER: S-EPMC2740816 | biostudies-literature | 2009 Feb
REPOSITORIES: biostudies-literature
Journal of molecular biology 20081211 1
Entry to sporulation in bacilli is governed by a histidine kinase phosphorelay, a variation of the predominant signal transduction mechanism in prokaryotes. Sda directly inhibits sporulation histidine kinases in response to DNA damage and replication defects. We determined a 2.0-A-resolution X-ray crystal structure of the intact cytoplasmic catalytic core [comprising the dimerization and histidine phosphotransfer domain (DHp domain), connected to the ATP binding catalytic domain] of the Geobacil ...[more]