Ontology highlight
ABSTRACT:
SUBMITTER: Takala SL
PROVIDER: S-EPMC2740818 | biostudies-literature | 2007 May
REPOSITORIES: biostudies-literature
Takala Shannon L SL Smith David L DL Thera Mahamadou A MA Coulibaly Drissa D Doumbo Ogobara K OK Plowe Christopher V CV
The American journal of tropical medicine and hygiene 20070501 5
Genetic diversity in malaria vaccine antigens may compromise malaria vaccine efficacy, so it is important to understand this diversity and the processes that generate it. By applying new high-throughput genotyping methods to a large sample of infections from Mali (N = 1369), seven new 19-kDa merozoite surface protein 1 (MSP-1(19)) haplotypes were identified. Herein we report the sequences of these new haplotypes and discuss their possible origins. Although they are present in < 1% of the samples ...[more]